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Centrum Pharmacy Blog

  • Unlocking the Clock: How Meal Timing Influences Cardiovascular Health and Longevity

    Eating meals earlier in the day has been associated with a reduced risk of cardiovascular disease, according to a recent study. The research, based on data from 103,389 individuals, emphasizes the importance of meal timing in the realm of chrononutrition. Beyond the content of our diets, the study highlights the significant impact of when we consume our meals on circadian rhythms and overall health.

    Previous studies have shown that delaying the first or last meal of the day may have adverse effects on cardiovascular health. A growing body of evidence in the field of chrononutrition suggests that not only what we eat but also when we eat plays a crucial role in maintaining good health. The timing of meals, coupled with exposure to light, influences circadian rhythms, affecting various aspects of health.

    Recent findings indicate that individuals who consume meals later in the day tend to burn calories more slowly and exhibit genetic changes that promote lipid storage, contributing to fat growth. Additionally, a study on diabetics revealed that restricting eating to a specific time window, from noon to 8 pm, resulted in greater weight loss compared to a conventional calorie-restricted diet. A mouse study from 2022 even demonstrated that restricting eating to the rodents’ most active nighttime hours extended their lifespans by 35%.

    The latest research, drawing from the NutriNet-Santé study, underscores the importance of breakfast timing. For every hour of delay in having breakfast, there was a 6% increase in the risk of developing cardiovascular disease. Comparing individuals who had their first meal at 7 am to those who ate at 10 am, the latter faced an 18% higher lifetime risk of cardiovascular disease. Furthermore, the study revealed that individuals eating their last meal after 9 pm experienced a 28% higher risk of cerebrovascular diseases, such as stroke and aneurysm, compared to those concluding their calorie intake before 8 pm.

    The medical information on this site is provided as an information resource only and is not to be used or relied on for any diagnostic or treatment purposes. This information does not substitute for professional diagnosis and treatment. Please do not initiate, modify, or discontinue any treatment, medication, or supplement solely based on this information. Always seek the advice of your health care provider first. Full Disclaimer: https://centrumpharmacy.com/disclaimer/ 

  • Embarking on adventures with Little Explorers – Factors to Consider When Traveling with Children

    Children possess distinct clinical and practical needs when on the move. To address these concerns, the following strategies for risk assessment and prevention should be followed:

    1. Book a Pre-Travel Consultation at Destinations Travel and Immunization Clinic for your family and get customised travel health advice from a professional who specializes in travel heath medicine. 
    2. Diarrhea:
    • Take food and water precautions.
    • Breastfeeding is optimal protection against food- and water-borne illnesses.
    • For formula-fed children, bring formula from home, and prepare with disinfected water.
    • Go to the travel clinic and get a standby prescription of Azithromycin for moderate or severe diarrhea.
    1. Insect Bites:
    • Use DEET 10% for teens or picaridin for children, varying in application frequency based on age.
    • For infants under six months, use for mosquito netting in high-risk areas.
    1. Sunburn:
    • Discourage direct sun exposure for infants under six months.
    • Use SPF ≥ 30 sunscreen if sun exposure is unavoidable, applied before insect repellent if both are required.
    1. Malaria:
    • Children are at a higher risk of severe complications, so see the travel clinic for a malaria chemoprophylaxis prescription.
    • Antimalarial options include atovaquone/proguanil, chloroquine, doxycycline (for children aged ≥ 8 years), mefloquine, or primaquine.
    • Antimalarials can be crushed for children who can’t swallow tablets and added to taste-masking foods.
    1. Other Considerations:
    • Be watchful for animal bites in countries with high rabies rates, considering children’s susceptibility.
    • Discuss the possibility of rabies vaccination for children at elevated risk.
    • Book a pre-travel consultation to review routine immunization status, including influenza and COVID-19 vaccinations at Destinations Travel and Immunization Clinic well before your trip.

    Resources for Families:

    • Travel for Kids: Family-friendly activities, destination-specific tips, and hotel recommendations.
    • Rough Guides: Travel ideas for children, packing advice, and transportation and accommodation options.
    • Travel.gc.ca: Canadian regulations and procedures for flying with children, including carry-on baggage, security screening, and using child restraint systems.
    • Sutter Health: Health advice for traveling with children.

    The medical information on this site is provided as an information resource only and is not to be used or relied on for any diagnostic or treatment purposes. This information does not substitute for professional diagnosis and treatment. Please do not initiate, modify, or discontinue any treatment, medication, or supplement solely based on this information. Always seek the advice of your health care provider first. Full Disclaimer: https://centrumpharmacy.com/disclaimer/ 

  • The World Health Organization (WHO) designated the JN.1 coronavirus strain as a “variant of interest”

    The World Health Organization (WHO) designated the JN.1 coronavirus strain as a “variant of interest” and indicated that, based on current evidence, the risk to public health from this strain is low. Despite its ability to evade the immune system and exhibit higher transmissibility compared to other circulating variants. Experts assert that JN.1 does not show any signs of causing more severe disease.

    While there may be an increase in cases involving the JN.1 variant, it is emphasized that it does not pose a greater risk. JN.1, initially considered a variant of interest within the BA.2.86 lineage, has now been classified separately by the WHO.

    The World Health Organization assured that existing vaccines remain effective in protecting against severe disease and death caused by JN.1 and other variants of the COVID-19 virus currently in circulation.

    According to the U.S. Centers for Disease Control and Prevention (CDC), as of December 8, the JN.1 subvariant constitutes an estimated 15% to 29% of cases in the United States. The CDC maintains that there is no current evidence suggesting an elevated risk to public health compared to other circulating variants. Additionally, it is stated that an updated vaccine could provide continued protection against the JN.1 variant.

    First detected in the United States in September, JN.1 has also been identified in seven cases in China, as reported last week.

    The medical information on this site is provided as an information resource only and is not to be used or relied on for any diagnostic or treatment purposes. This information does not substitute for professional diagnosis and treatment. Please do not initiate, modify, or discontinue any treatment, medication, or supplement solely based on this information. Always seek the advice of your health care provider first. Full Disclaimer: https://centrumpharmacy.com/disclaimer/ 

  • Zonnic Nicotine Patches : Most Effective Nicotine Replacement Therapy or an Elaborate Scheme by Big Tobacco?

    Zonnic Nicotine Patches : Most Effective Nicotine Replacement Therapy or an Elaborate Scheme by Big
    Tobacco?
    Zonnic nicotine pouches entered the market in mid-October, sparking immediate controversy. The
    Health Minister and health organizations have raised objections, while the manufacturer contends that
    the product is unfairly maligned.
    Crafted by Imperial Tobacco Canada, Zonnic nicotine pouches aim to serve as nicotine replacement
    therapy (NRT) for smokers. Health Canada granted approval for their sale in July under Natural Health
    Product Regulations, given their nicotine content without tobacco. Packaged in vibrant, “attractive-to-
    youth” containers resembling gum. They come in three flavors: Tropic Breeze, Chill Mint, and Berry
    Frost. Users place a pouch under their lip, releasing 4 mg of nicotine slowly. These pouches are available
    in convenience stores, gas stations, and pharmacies.
    Studies have found that oral nicotine pouches compared favorably to other NRTs, with users reporting
    fewer minor adverse events and greater satisfaction than with nicotine lozenges or gum.
    Despite these positive findings, six national health organizations have called for a change in regulations,
    arguing that the approval was a mistake. They highlight concerns that Zonnic can be legally sold to
    minors of any age and can be promoted through billboards, advertising, and free samples. Health
    Canada, in response, emphasizes the importance of preventing youth access and is considering
    regulatory options.
    The health groups advocate for reclassifying Zonnic as a prescription product or banning its sale. They
    also call for a temporary halt on approvals for similar nicotine pouches or new nicotine product
    categories.
    Imperial Tobacco Canada asserts that Zonnic targets adults and emphasizes self-regulation, ensuring
    sales only to those over 18 with proof of age. However, health groups argue that, despite restrictions on
    sales, there are no legal penalties for retailers selling it to minors.
    The advertising approach is under scrutiny, with concerns that Zonnic's ads, emphasizing lifestyle, are
    likely to reach children. Health Canada specifies that NRT labels and advertisements should prominently
    indicate their intended use for smoking cessation in adults.
    The Health Minister expresses concerns about the tobacco industry's intentions, while Imperial Tobacco
    Canada defends Zonnic's efficacy and safety for smoking cessation. The ongoing debate raises parallels
    with past challenges in regulating vaping, and health advocates stress the need for robust regulatory
    frameworks to prevent potential risks associated with new nicotine products.

    The medical information on this site is provided as an information resource only and is not to be used or relied on for any diagnostic or treatment purposes. This information does not substitute for professional diagnosis and treatment. Please do not initiate, modify, or discontinue any treatment, medication, or supplement solely based on this information. Always seek the advice of your health care provider first. Full Disclaimer

  • ‘Tis the Season

    ‘Tis the season for festive gatherings and holiday cheer. These occasions hold significance in fostering a sense of community, contributing to mental well-being, and bringing people together. However, the convergence of respiratory viruses during this time, especially amid the winter months, poses a
    heightened risk of transmission.

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  • Regular Marijuana Use Linked to Increased Heart Failure Risk

    Recent observational research presented at the American Heart Association (AHA) 2023 Scientific Sessions reveals a 34% higher risk of heart failure within four years associated with daily marijuana use compared to non-use. The findings, while observational and indicating association rather than causation, contribute to a growing body of evidence on the potential cardiovascular effects of marijuana. 

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  • A History of Military Service by Pharmacists

    This Remembrance Day, We at Centrum Pharmacy would also like to inform you of the roles and services that Pharmacists in the military have played and continue to play in safeguarding our troops and ultimately our freedom. 

    History of Pharmacists in the Military: 

    This history lesson highlights the indispensable role pharmacists have played in various wars, from World War II to modern conflicts. 

    World War II: The Unsung Heroes: Pharmacists faced dangers of combat, with individuals like Robert Knecht and Paul Stanley Frament losing their lives. Despite the risks, wounded soldiers expressed gratitude for the vital role played by medics, including pharmacists.

    Early Challenges: 1930s-1940s: Pharmacy education required a baccalaureate degree, but this didn’t grant a military commission. The value of pharmacists wasn’t always aligned with their rank and pay. Ultimately, a dispensing error in 1930 highlighted the need for employing skilled pharmacists in the military.

    Recognition and Struggle: In 1943, President Roosevelt established the Pharmacy Corps in the Army. Approximately 14,000 pharmacists or students served during WWII. Post-war, the Pharmacy Corps was replaced by the Medical Service Corps in 1947.

    Korean War: Advancements and Opportunities: The Korean War saw advancements in pharmacy and pharmaceuticals. Pharmacists contributed to formulary development, and pharmacy officers played a crucial role in intravenous fluid therapy.

    Postgraduate Training and Recognition: In the late 1950s and early 1960s, pharmacy officers competed for postgraduate training. In 1958, the first master’s degree program in hospital pharmacy was completed. In 1966, the Secretary of Defense mandated that major military medical treatment facilities must be staffed with licensed pharmacists.

    Vietnam War: Controversy and Improvement: The Vietnam War sparked controversy, but military medical services improved in specialization and speed. Pharmacists played crucial roles in medical evacuation systems, highly trained medical specialties, and biomedical research.

    Modern Era: Clinical Pharmacy and Combat Deployment: In the 1980s, clinical pharmacy took shape, and the Pharm.D. degree became recognized for promotion. The 1990s saw the establishment of clinical pharmacy practices. Operations Desert Shield, Desert Storm, Somalia, Haiti, and Bosnia provided pharmacists with opportunities in combat deployments.

    Present Day: Homeland Security and Unified Forces: All branches of military medicine work jointly for homeland security. Pharmacists are responsible for pharmacy operations, personnel, and entire ambulatory healthcare facilities. They play a significant role in medication logistics, inventory activities, and homeland defense readiness.

    Conclusion: Military pharmacists, in wartime and peacetime, continue to play a crucial role in protecting the country. Their sacrifices deserve honor and respect, in all its aspects.

  • The Role of Pharmacists in the Military

    This Remembrance Day, We at Centrum Pharmacy, would also like to inform you of the crucial roles and services that pharmacists in the military play in safeguarding our troops and ultimately our freedom. 

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  • Cardiovascular Disease Research in Women: Underrepresented and Underdiagnosed

    Cardiovascular disease (CVD) stands as the primary global cause of death, accounting for approximately 17.9 million fatalities in 2019. In Canada, it ranks as the second leading cause of death for both men and women, with heart disease and stroke emerging as the top culprits for premature female mortality. Notably, the manifestation of heart disease differs between genders; women commonly exhibit microvascular disease in smaller vessels, while men tend to experience macrovascular disease in larger vessels. Consequently, the symptoms presented by women may vary from those observed in men. Hormone-related changes, specific medical conditions, and medications unique to women can also influence CVD development. Unfortunately, research studies have not consistently included women, resulting in unequal representation and potentially disparate treatments upon diagnosis. Addressing this gap requires further studies and enhanced educational efforts tailored to women, recognizing their distinct experiences with CVD, characterized by smaller vessel involvement and specific risk factors. Here is a breakdown:

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  • Tai Chi and its Effects on the Brain, particularly for the Elderly

    I have long advocated tai chi as a form of exercise, especially for the elderly and for individuals with physical challenges that make conventional aerobic exercises difficult to perform. If you’ve never done tai chi, which is a martial art that incorporates a series of movements, known as forms, with a focus on controlled breathing. It may look like nothing much is happening, but that’s a misconception. In fact, you are actually working very hard, and the physical benefits are pronounced. Many studies have shown that practicing tai chi can also help prevent falls and improve balance in older adults, and the benefit is greatest for people who keep up a regular practice over time.

    There has always been a suggestion that Tai Chi also has a beneficial effect on the brain and for maintaining mental acuity. Finally, there is a controlled study that seems to back up those claims:

    Tai chi is not just a physical exercise; it’s a mental workout too! A recent study shows that practicing tai chi can significantly slow cognitive decline and protect against dementia, especially for older adults.

    The study involved approximately 300 older adults, with an average age in their mid-70s, who reported experiencing a decline in their memory. All participants took a cognitive function test called the Montreal Cognitive Assessment, where a normal score ranges from 26-30. The average score at the beginning of the study was 25, indicating mild impairment.

    The findings revealed that those who practiced a simplified form of tai chi called Tai Ji Quan twice a week for six months improved their cognitive test scores by 1.5 points. While it may seem like a modest increase, study author Dr. Elizabeth Eckstrom emphasizes that it’s akin to giving oneself three extra years of staving off cognitive decline.

    For those engaged in a more rigorous type of tai chi, known as Cognitively Enhanced Tai Ji Quan, which involves additional challenges like spelling words backward and forward during tai chi moves, the improvement was about 3 points. This translates to giving individuals an extra six years of cognitive function.

    The study suggests that the memorization of tai chi movements, combined with fluid mind-body coordination, contributes to its effectiveness in preserving cognitive function. This combination of physical activity and memory engagement appears to be a winning formula.

    Dr. Joseph Quinn, a neurologist not involved in the study, finds the results impressive, even though he admits not fully understanding why tai chi works so well. He speculates that the meditative component and stress reduction effect could be contributing factors.

    Participants in the study expressed the meditative nature of tai chi, describing it as a practice that helps them feel grounded, release stress, and improve concentration. Beyond the cognitive benefits, tai chi has long been recognized for its impact on balance and fall prevention in older adults.

    While the study predominantly involved non-Hispanic white participants with college degrees, researchers acknowledge the need for efforts to make tai chi more accessible to a broader population, especially considering the disproportionate burden of cognitive impairment among certain demographic groups.

    In essence, tai chi isn’t just a series of graceful movements—it’s a dance for the mind and body, providing not only physical benefits but also a powerful defense against cognitive decline.